Study Unveils Potential Treatment for Spinal Muscular Atrophy

Thursday, February 25, 2016
From left to right: Microscopic images comparing the hind leg muscles of normal mice, mice with spinal muscular atrophy, and mice with spinal muscular atrophy that have had the enzyme JNK3 inhibited. JNK3 deficiency appears to reduce muscle degeneration (muscle-wasting) and increase muscle growth in mice with the disease. Image courtesy of the journal Human Molecular Genetics.

Neuroscientists have discovered a specific enzyme that plays a critical role in spinal muscular atrophy, and that suppressing this enzyme’s activity, could markedly reduce the disease’s severity and…

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