PodMed TT – Monitoring Glucose to Identify Diabetes Subtypes

What can we learn from continuous glucose monitoring for a few weeks and standardized food challenges among people who haven’t been diagnosed with diabetes? A lot, as Rick and I discuss on PodMedTT this week.

The study, published in Public Library of Science Biology, looked at 57 subjects whose blood glucose was continuously monitored for two to four weeks. Each of them was also fed three standardized breakfasts twice: cornflakes and milk, a peanut butter sandwich and a protein bar. The plethora of data revealed new categories of what the authors call “glucotypes” based on how their blood glucose varied and how they responded to the meals.

Of great interest is the fact that many of these folks would fit the bill for prediabetes, and therefore be at risk of frank diabetes. In addition, the spike in blood glucose relative to consumption of cornflakes and milk caused the authors to speculate that such a meal is unsuitable for an estimated 80 percent of the world’s population. Finally, Rick and I agree that very much like a continuous blood pressure monitoring study we reported a few months ago, this study makes the case for continuous monitoring to obtain a more accurate picture of a person’s physiology.

Other topics this week include genomic screening and health care, and use of an anti-inflammatory for dilated cardiomyopathy in Annals of Internal Medicine; and firearm caliber and death in JAMA Open.

Until next week, y’all listen up and make healthy choices.