The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Texas Tech University Health Sciences Center El Paso Co-Principal Investigators Richard McCallum, M.D., and Irene Sarosiek, M.D., with $466,000 to support their gastroparesis research and team. The grant was originally awarded in 2008 and a new five year renewal was successfully granted in 2012.
The National Institutes of Health Consortium on Gastroparesis was initiated by NIDDK and constitutes eight national centers performing basic, translational, and clinical-therapeutic research on gastroparesis patients of diabetic and idiopathic etiologies. A database of more than 600 patients – the world’s largest registry – will be followed longitudinally and participate in studies examining serology, genetic, gastric tissue histology of smooth muscle and nerves and cutting edge treatment protocols. One such study for the relief of nausea is underway with El Paso being the highest enrolling site in the country.
Additionally, there is a diabetes specific study in which continuous glucose monitoring and insulin pump therapy is used in reducing symptoms of diabetic gastroparesis.
A translational trial of tricyclic neuromodulators has been published in JAMA in January 0f 2014. The NIDDK has made a commitment to supporting gastroparesis of diabetic origin as a priority and the citizens of El Paso are the beneficiaries.