PodMed TT – Cannabis Use and Cognition

Does cannabis use affect cognition? That’s a really important question as both medical and recreational marijuana use spreads across the country. A study in JAMA Psychiatry Rick and I discuss on PodMed TT this week appears to offer some hope to those who are concerned about marijuana use among younger folks, whose brains are still developing new pathways. The study comes to the conclusion that cognition in this group of late teens and early twenties is not impacted by the use of cannabis. But slow down, we caution. Major constraints exist in this study design. It’s a meta-analysis, and its most robust conclusion was that cognition was not impacted if measurements were done 72 hours after the most recent cannabis exposure. Hmmm. As for us, we’d be much more comfortable with a prospective study, or at least one with multiple measurements over time. Failing that, we no doubt will have a number of observational studies coming to fruition shortly.

Other topics this week include Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study in BMJ; Effect of Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency 1 Year After Coronary Artery Bypass Grafting in JAMA; and A Randomized Trial of Early Endovenous Ablation in Venous Ulceration in NEJM.

Until next week, y’all listen up and make healthy choices.